Laboratory Manager (Immunology Platform)
Position Code: LM -523
Reports to: Head of Platform
Station: Entebbe

Job Purpose
The position holder will be responsible for organizing the platform workflow and facilities allocation to users to maximize efficiency, speed, and quality and cost control for all projects.

Roles & Responsibilities
1. Principal Duties;
• Supervises Platform maintenance and organises QC, calibrations, equipment maintenance and maintenance controls;
• Keeps stock inventory and reorders consumables/reagents, verifies delivery and liaises with suppliers on quality, performance and cost issues;
• Keeps track of SOPs in use in the lab and acts as a central reference;
• Keeps central records of all Platform equipment and their location;
• Assists with special technical, logistics and coordination problems associated with running the Platform;
• Supervises all users of Platform equipment, signs off users as competent for all equipment;
• Evaluates existing procedures for possible improvements in reliability and efficiency;
• Applies GLP and verifies audit preparedness; and,
• Follows safety procedures and checks, keeps COSHH documentation for all reagents, supervises induction of new users and keep training records. 2. Financial Management Duties.
• Accountability for and close monitoring of Platform expenditure and recoveries;
• Defines specifications and obtains quotes for procurement of consumables and equipment. Prepares orders and manages Platform budget;
• Arranges service contracts for preventive maintenance of all equipment;
• Issues invoices for services provided by the Platform (e.g. use of flow cytometer or ELISPOT reader); and,
• Works with the quality manager to support internal and external audits.

Person Specification
• MSc in a laboratory science, or equivalent;
• GCLP training/ current Allied Health Professions licence;
• Should possess more than two years’ experience in a clinical/research laboratory;
• Experience in biomedical laboratory and working to GCLP standards; ,
• Previous experience in working in a laboratory Clinical Trials environment;
• Extensive practical experience across the major medical laboratory disciplines;
• Experience with IATA or an IATA certification;
• Experience managing and supporting different teams;
• Experience working in collaboration with external regulatory agencies;
• Demonstrable experience in administration and resource management;
• Experience of flow cytometry techniques, Cytometer usage and machine management;
• Should possess knowledge of GCP/GCLP;
• Knowledge of safety regulations;
• Provision of high quality training and supervision to staff and students;
• Lead quality assurance programs;
• Independent assay development & troubleshooting of new procedures;
• Knowledge or experience of Spectral Flow Cytometry; and,
• Knowledge and experience of flow cytometry analysis;

Statistician
Position Code: S -523
Reports to: Head of Statistics
Station: Entebbe

Job Purpose
The position holder will provide support to the Impala and Malaria trials data management and statistical team ensuring the trials data is reviewed at all times and conform to the Investigators specifications. He/she will from time to time be required to carry out statistical analysis and generate some reports relating to the trial results.

Roles & Responsibilities
1. Principal duties;
• To provide data management and statistical support to the trials statisticians and data managers for the main Impala and Malaria trials and associated studies;
• Maintaining close collaborative links with statisticians and other researchers at MRC/UVRI & LSHTM Uganda Research Unit as well as with other international partners;
• To contribute to the management of ongoing studies;
• To collaborate with data managers and provide a statistical perspective on designing and setting up study databases and data processing;
• To perform statistical analysis of project-collected data;
• To contribute to the development and preparation of protocols and data collection instruments for new research studies;
• To develop statistical analysis plans for ongoing trials and to organise and prepare for milestone events such as database lock, unblinding, analysis and reporting;
• To prepare regular checks on study data to help project management teams monitor recruitment and other data flows and data quality issues during the conduct of a study;
• To conduct interim analyses for data monitoring committees and trial steering committees;
• To prepare scientific reports and present results in meetings with colleagues and collaborators;
• To development scientific articles and prepare publication-standard tables and figures;
• To contribute to the Statistics section's collegial environment including through teaching and training activities and participation in regular academic/journal club meetings; and,
• To undertake additional tasks as required by the Principal Investigator or Head of Statistics or assigned supervisor.

Person Specification
• Master’s degree in medical statistics or closely related subjects e.g. epidemiology and mathematics;
• Should possess practical experience as an applied medical statistician;
• Strong analytical skills and a good understanding of statistical issues in medical research;
• Should have excellent statistical programming skills using STATA or equivalent statistical analysis software; and,
• Strong computer skills including proficiency with Microsoft Office applications and in particular with Excel and Word;